https://www.rollingstone.com/tv-movies/tv-movie-news/christina-applegate-no-multiple-sclerosis-1235645349/
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““She came into my room and said, ‘Congratulations, you don’t have MS,'” Applegate said.”
“Matt Winkelmeyer/Getty Images/Critics Choice Association Five years after Christina Applegate ‘s doctors told her that she had multiple sclerosis , they’re now telling her she never had the autoimmune disorder.”
““You don’t get misdiagnosed and then all of the sudden I’m better,” Applegate said.”
““And a majority of them were on medication to treat their MS.” Multiple sclerosis damages the protective cover around one’s nerves, according to the Cleveland Clinic .”
“And now I don’t have a reason and it’s very unnerving and it’s very confusing for me.” She described her present state as “the same game with a different name.” Applegate said she feels like her symptoms have gotten worse since she learned the news.”
“The actress revealed the news on MeSsy , her MS-themed podcast she hosts with Jamie Lynn Sigler, who has MS, since March 2024.”
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“Account Welcome Manage Account Manage Print Account Sign Out Log In 'State of Shock' Christina Applegate Says She Was Misdiagnosed With Multiple Sclerosis: ‘It’s Very Confusing’ "You don't get misdiagnosed and then all of the sudden I'm better," actress says on MeSsy podcast By Kory Grow Kory Grow Contact Kory Grow on X Christina Applegate Says She Was Misdiagnosed With Multiple Sclerosis: ‘It’s Very Confusing’ Sharon Osbourne Talks Ozzy’s ‘Back to the Beginning’ Film: ‘He Went Out Like a Viking’ Alice Cooper Is Finally Ready to Tell the Truth View all posts by Kory Grow October 20, 2026 Add us as a Google Preferred Source Christina Applegate, 2023.”
“Marwa Kaisey, who works in Cedars-Sinai Medical Center’s neurology department, spoke on the podcast saying misdiagnoses are “fairly common” since there is no single binary MS test saying whether a patient definitely has or doesn’t have the disorder.”
“She said she’s in a “state of shock” over the news, which she calls a “mindfuck.” What’s most frustrating for Applegate, though, is that she’s still has symptoms that no longer have an explanation and that she feels she accidentally misrepresented herself to those with the disorder, according to People .”
““I’ve gone through a great depression because of [the misdiagnosis],” Applegate said on MeSsy .”
“On back-to-back episodes of the podcast, Applegate explained that she took a leave of absence from the podcast in March while she processed her doctor’s news.”
““But I lost everything.”
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“She added that she expects her doctors to investigate how and why she was misdiagnosed.”
““It’s this weird feeling because I became this — you [Sigler] and I, the poster children for MS.”
“She teared up onstage in 2024 when she received a standing ovation at the Emmys while presenting an award .”
“Editor’s picks The 250 Greatest Albums of the 21st Century So Far The 100 Best TV Episodes of All Time The 500 Greatest Albums of All Time 100 Best Movies of the 21st Century “I still have to use wheelchairs when I go to the doctor’s office,” she said.”
“Nothing magical happened when she said, ‘You don’t have MS.’ Nothing magical happened.” Applegate has spoken at length about MS, saying in 2024 that she believed she had been suffering from the disorder at least six or seven years prior to the 2021 diagnosis.”